Home › Guides

What a 10-Panel Drug Test Screens For

A 10-panel drug test is a lab urine test that screens for a set list of drug groups. Pact's 10-panel is Quest Diagnostics unit code 65190N. It covers amphetamines, barbiturates, benzodiazepines, cocaine, marijuana, methadone, methaqualone, MDMA/MDA, opiates, oxycodone, PCP and propoxyphene. It does not test for alcohol. This guide lists every drug on the panel, explains why other sellers' 10-panels can look different, and covers what happens if you take a prescription.

Updated October 16, 2026 · Checked against the official sources listed at the end

The drugs on Pact's 10-panel

Quest Diagnostics publishes a sheet of its commonly ordered urine panels. Unit code 65190N is listed there as the "10 Panel DOT look-alike." Here is what the sheet lists for it:

Amphetamines: amphetamine and methamphetamine.
Barbiturates: amobarbital, butalbital, pentobarbital, phenobarbital and secobarbital.
Benzodiazepines: confirmed as alprazolam metabolite and oxazepam.
Cocaine metabolites.
Marijuana metabolites (THC).
Methadone.
Methaqualone.
MDA-analogues: MDMA (ecstasy) and MDA.
Opiates: codeine and morphine, plus 6-acetylmorphine.
Semi-synthetic opiates: hydrocodone and hydromorphone.
Oxycodones: oxycodone and oxymorphone.
Phencyclidine (PCP).
Propoxyphene.

How the lab screens and confirms

Quest tests a urine specimen in two steps. The first step is a screening test on one portion of the specimen. It sorts out negative specimens quickly. If a screen is not negative, a confirmation test is run on a different portion of the specimen. Quest says confirmation tests use gas or liquid chromatography with mass spectrometry, which can identify the specific drug.

Each drug has a cutoff level for each step. For example, Quest's sheet lists a screening cutoff of 50 ng/mL for marijuana metabolites and a confirmation cutoff of 15 ng/mL.

Quest's sheet also lists its TestSure specimen validity testing with this panel. Quest says this checks pH, creatinine and specific gravity (when indicated) and tests for substances added to the urine.

Why 10-panel lists differ between sellers

"10-panel" is a common name, not a fixed standard for non-DOT tests. Quest's own FAQ says there are hundreds of combinations of drugs, order codes and cutoff levels, so there is a urine panel for almost any testing reason.

Quest's sheet shows this. It lists an older "10 Panel pre 2010 DOT look-alike" (unit code 35190N) with ten groups: amphetamines, barbiturates, benzodiazepines, cocaine, marijuana, methadone, methaqualone, opiates (codeine and morphine), PCP and propoxyphene. The current 65190N panel keeps those and adds MDMA/MDA, 6-acetylmorphine, hydrocodone and hydromorphone, and oxycodone and oxymorphone.

So two companies can both sell a "10-panel" and test for different drugs. If your employer or program gives you a list of drugs it wants tested, compare it with the list above before you order. If it names a specific testing company, use that company.

Does a 10-panel test for alcohol?

Not this one. Quest's sheet for 65190N lists no alcohol test, and Pact's 10-panel does not include one. If an employer or program also wants an alcohol test, ask them what kind of test they accept.

10-panel vs the DOT drug test

"DOT look-alike" is Quest's name for the panel. It does not make the test a DOT test. A DOT drug test checks for five drug classes set by federal rule: marijuana, cocaine, amphetamines, opioids and PCP (49 CFR 40.82). The same rule says labs must not test DOT specimens for any other drugs.

DOT tests must also be kept completely separate from non-DOT tests (49 CFR 40.13). Pact's 10-panel is a non-DOT test. If DOT rules cover your job, your employer has to order a DOT test. See our guide to the DOT drug test panel for what that test covers.

Prescriptions and MRO review

You don't list your medicines at the collection site. Quest's instructions for donors say the collector will not note any prescription drugs on the chain of custody form.

Instead, a lab result on Pact's 10-panel that is not negative goes to a medical review officer (MRO). The MRO is a licensed physician who contacts the person tested to ask about prescriptions before the result is final. Keep your phone on and have your prescription details ready. Our MRO guide explains how that review works.

Common questions

Does a 10-panel drug test test for alcohol?

Pact's 10-panel (Quest unit code 65190N) does not. Quest's published list for that panel has no alcohol test.

Does Pact's 10-panel include oxycodone?

Yes. Quest's sheet lists oxycodone and oxymorphone under the oxycodones group for 65190N, along with hydrocodone and hydromorphone.

Does it test for fentanyl?

Fentanyl is not on Quest's published list for unit code 65190N.

Is a 10-panel the same as a DOT drug test?

No. A DOT test covers five drug classes under 49 CFR 40.82 and must be kept separate from non-DOT tests. Pact's 10-panel is a non-DOT test and can't replace a DOT test your job requires.

Should I tell the collector about my prescriptions?

Quest says its collector will not note prescription drugs on the custody form. If your lab result is not negative, the medical review officer will contact you and ask about prescriptions before the result is final.

How much is Pact's 10-panel?

$40. That covers the urine collection at a Quest Diagnostics patient service center, the lab test and MRO review.